منابع مشابه
Glutathione S-transferases Null Genotype in Acute Myeloid Leukaemia
Background: The glutathione S-transferase (GST) family of metabolising enzymes plays an important role in the detoxification of mutagens and carcinogens. The expression of many of these cancer susceptibility enzymes is genetically polymorphic. An increased frequency of GST-null genotypes has been associated with several malignancies. Objective: To investigate the rate of GSTT1 and GSTM1 null ge...
متن کاملThe induction of myeloid leukaemias by Rauscher murine leukaemia virus.
A number of cloned viral preparations isolated from Rauscher virus-producing JLS-V5 cells were compared in their competence to induce different types of leukaemias. All preparations were able to induce myeloid leukaemias, but the induction of lymphatic or erythroid leukaemias was also observed. Serial infection of newborn mice with either cell-free extracts or serum from animals suffering from ...
متن کاملMyeloid leukaemia.
This study was supported by the All India Institute of Medical Sciences, the Directorate General Armed Forces Medical Services, and the Indian Council of Medical Research, New Delhi. We are grateful to Lt.-Gen. S. N. Chatterjee, Director-General Armed Forces Medical Services, and Lt.-Gen. Ved Prakash, Director Medical Services (Army), and their staff for ungrudging support during all phases of ...
متن کاملExpression Profiling of Microarray Gene Signatures in Acute and Chronic Myeloid Leukaemia in Human Bone Marrow
Background Classification of cancer subtypes by means of microarray signatures is becoming increasingly difficult to ignore as a potential to transform pathological diagnosis nonetheless, measurement of Indicator genes in routine practice appears to be arduous. In a preceding published study, we utilized real-time PCR measurement of Indicator genes in acute lymphoid leukaemia (ALL) and acute m...
متن کاملleukaemia, myelodysplastic syndromes, and chronic myeloid leukaemia
Introduction The standard approach to the diagnosis of acute leukaemia and myelodysplasia has been based on the morphology and percentage of malignant haemopoietic cells in peripheral blood and in an aspirated sample of bone marrow. The FAB group reports on acute leukaemia have emphasised the value of additional information gained from cytochemistry,' and immunological studies and cytogenetics ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1970
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1970.75